I finally got the radio hooked up through my XP computer at home.
I switched the USB to another port and it finally saw the radio and programming was a breeze.
I still couldn't get it to connect to my Windows 7 computer at work after trying everything and installing and re-installing drivers.
I followed these directions and it connected right up.http://www.miklor.com/uv5r/UV5R-Drivers.html
WOW, a week of frustration and finally got it connected.