I recently bought my first mobile VHF/UHF radio. I had previously been using an Icom 706MKIIG for this, but wanted the freedom of running full-time VHF/UHF while also running HF. In any event, I compared the various radios available and bought the FT-8800R. I have only had it a couple of months so far, but I have no complaints.
Interestingly, I also wanted to time-share my 8800 between the house and 2 vehicles. I knew that moving the radio back and forth between the house and the car would get old, so I wanted an installation that allowed me to remove the radio easily. What I did was to make my own mounting bracket out of aluminum that holds the radio pretty securely without requiring that the radio be bolted to the bracket. The bracket is lined with thick felt that holds the radio pretty securely (and captivates it to prevent any "extreme movement" in the forward or lateral directions in the event of a crash). I made one bracket for my car and another for my shack. The radio just slides in and sits in the bracket, so it's pretty easy to move back and forth. The brackets have a "backstop" that the rear of the radio sits against without blocking access to any of the rear-panel connectors. I cut the Yaesu power connector off my 8800R and installed an Anderson Powerpole instead. This makes it somewhat universal with the rest of my stuff and provides a quick-disconnect capability. Obviously, to keep things simple, I opted to mount the 8800R as one unit instead of separating the main body from the control head. I did the opposite with my 706, which stays in the mobile nearly 100% of the time.
My brackets are kind of beefy, but the radio comes out or goes in in seconds, so I'm able to easily share the radio between two locations. Even so, moving the radio back and forth gets old quickly. If you are counting on moving the radio back and forth every day, be forewarned. Mine already stays mostly in the mobile. I put a conventional bracket (i.e. that holds the radio with bolts) in my second vehicle, which we use for longer trips.
You can see a photo of the radio/bracket at:http://img.photobucket.com/albums/v281/jdcphotos/ab5cc738.jpg
The 8800R is the lower radio, of course. The bracket does not obsctruct airflow over the heat fins, doesn't block the mic port or any other connectors, and allows sufficient space above the speaker to allow the audio not to get blocked.
There are countless ways of doing these kinds of things. This one was mine. Good luck.
Dave / K8JDC