I'm using the cable that came with the radio. It goes directly from the radio to to USB and plugs into the USB port on the computer.
Yes, having trouble with both CHIRP and the VIP software that came with the radio,
I tried both reading and writing and getting no radio connected errors on both CHIRP and VIP.
Try reloading the USB driver and then make sure you selecting that port in the software. Also, make very sure the cable is inserted fully into the radio - I had a problem with that in the past.