I've had an FTM-400 for over a year. I bought the radio mainly for APRS, particularly the touchscreen that gives you a keyboard to enter text messages. I use this function frequently when I'm working in areas with no cell coverage. I can send text messages, thru the SMS gateway, directly to my wife's cell phone. The radio works just fine for this. I like it. I have not tried to interface a computer to the rig as I'm not interested in that. The GPS receiver seems to work very well. I have the newer model, not the original one with the slow GPS receiver. The receive audio is quite loud, even in my diesel work truck.
As far as a radio the only bad thing I can say is there is no way to divide up the memories into banks. There are 500 memories per band. You have to scroll thru all of them to get to what you want. I typically roam around a rather large area and have lots of repeaters programmed in. It would be nice to have them in different banks for different areas.