I'm a mixed knob/button, mouse/touch screen type myself. I prefer a computer interface overall, with one exception: the main VFO. For that I have a USB device that has a big knob and rotary encoder that I use to tune the bands. I do everything else via the computer interface using the mouse, keyboard, and touch screen.
Ditto for test instruments. I prefer a PC-based 'scope like a Picoscope over a knob-based 'scope from Tek or Keysight.
The biggest advantage to being PC-based is screen size and resolution. Rigs like the 7300 and 7610 have small screens in the 4-7" range with limited resolution. For PC rig control, I use three 32" 4K screens. Sure, the 7610 has a port for an external display, but it's limited to displaying exactly what's on the internal screen at exactly the same resolution (plus Icom was too cheap to spring for an HDMI license, so they used the ancient DVI interface). The K4, on the other hand, has an HDMI interface and isn't restricted to displaying what's on the built-in screen.