When considering any specific vehicle such as Ford F150,
There are several different engine options and many different body equipage function options that can be present depending on the model level such as XL, XLT etc.
The interference sources present many possibilities.
A. Going negative to the battery terminal puts a Battery management sensor between the neg. terminal and the Chassis for ground.
B. There is a tire pressure monitoring system usually in the 313 band, the remote-control system in the 915 band, ABS monitoring, The dash big screen operations, the PCM clock frequency and the list goes on and on with over30 different modules on communication Bus, all over the vehicle. Many of the functions are in one module located in right rear cab roof area over the head liner.
Ignition on a 5L v8 engine has 7 coil overs and one offset coil linked to the #3 spark plug by a short, exposed lead and boot.
Full electronic dash displays.
Often owners substitute Halogen Lamps with LED and get issues from the peticular LED chosen for the change if it is internal switch driven with resultant hash interference.
....You need to make a good attempt to ID the source, see what the solution to that specific interference source might be and go from there.
....Might be informative to look at page 583 of the 2018 Owner manual for RF field specs as additional Radio info.
ID the source, then what to do about it.
If the Dash display includes AM radio, check to see if you hear RFI on that unit.
Modern vehicles no longer fit the old standards for interference sources and remedies.
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I run 2m FM and reverse turns on the backup camera function and Dash display screen and overloads the radio but is not an issue for the small time in reverse.
2018 5L XLT.
Good luck.